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The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function

The relative activity of regulatory versus conventional CD4(+) T cells ultimately maintains the delicate balance between immune tolerance and inflammation. At the molecular level, the activity of phosphatidylinositol 3-kinase (PI3K) and its downstream positive and negative regulators has a major rol...

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Detalles Bibliográficos
Autores principales: Han, Jonathan M., Patterson, Scott J., Levings, Megan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417165/
https://www.ncbi.nlm.nih.gov/pubmed/22905034
http://dx.doi.org/10.3389/fimmu.2012.00245