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The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function
The relative activity of regulatory versus conventional CD4(+) T cells ultimately maintains the delicate balance between immune tolerance and inflammation. At the molecular level, the activity of phosphatidylinositol 3-kinase (PI3K) and its downstream positive and negative regulators has a major rol...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417165/ https://www.ncbi.nlm.nih.gov/pubmed/22905034 http://dx.doi.org/10.3389/fimmu.2012.00245 |