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The SK2-Long Isoform Directs Synaptic Localization and Function of SK2-containing channels

SK2-containing channels are expressed in the postsynaptic density (PSD) of dendritic spines on mouse CA1 pyramidal neurons, and influence synaptic responses, plasticity, and learning. The SK2 gene encodes two isoforms differing only in the length of the N-terminal domain. SK2-Long (SK2-L) and SK2-Sh...

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Detalles Bibliográficos
Autores principales: Allen, Duane, Bond, Chris T., Luján, Raphael, Ballesteros-Merino, Carmen, Lin, Mike T., Wang, Kang, Klett, Nathan, Watanabe, Masahiko, Shigemoto, Ryuichi, Stackman, Robert W., Maylie, James, Adelman, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417338/
https://www.ncbi.nlm.nih.gov/pubmed/21602822
http://dx.doi.org/10.1038/nn.2832