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Alpha-1 Antitrypsin is Markedly Decreased Following Pulmonary F. tularensis Challenge

Neutrophils form the first line of defense during infection and are indispensable in this function. The neutrophil elastase is a key effector molecule of the innate immune system with potent antimicrobial activity against Gram-negative bacteria, spirochaetes, and fungi. However, the release of neutr...

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Detalles Bibliográficos
Autores principales: Chambers, James P., Yu, Jieh-Juen, Jupelli, Madhulika, Weintraub, Susan T., Lopez-Ribot, Jose L., Valdes, James J., Arulanandam, Bernard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417364/
https://www.ncbi.nlm.nih.gov/pubmed/22919586
http://dx.doi.org/10.3389/fcimb.2011.00020