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Immunogenic Response of Brucella canis virB10 and virB11 Mutants in a Murine Model

The virB locus, which encodes the type IV secretion system, is a major component of virulence in Brucella. A non-polar virB10 mutant and a virB11 deletion mutant were constructed in Brucella canis. In the mouse model, both mutants were cleared at day 21 post-infection, indicating reduced virulence i...

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Detalles Bibliográficos
Autores principales: Palomares-Resendiz, E., Arellano-Reynoso, B., Hernández-Castro, R., Tenorio-Gutiérrez, V., Salas-Téllez, E., Suárez-Güemes, F., Díaz-Aparicio, Efrén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417389/
https://www.ncbi.nlm.nih.gov/pubmed/22919627
http://dx.doi.org/10.3389/fcimb.2012.00035