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Immunogenic Response of Brucella canis virB10 and virB11 Mutants in a Murine Model
The virB locus, which encodes the type IV secretion system, is a major component of virulence in Brucella. A non-polar virB10 mutant and a virB11 deletion mutant were constructed in Brucella canis. In the mouse model, both mutants were cleared at day 21 post-infection, indicating reduced virulence i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417389/ https://www.ncbi.nlm.nih.gov/pubmed/22919627 http://dx.doi.org/10.3389/fcimb.2012.00035 |