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Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila

Helicobacter pylori strains containing the CagA protein are associated with high risk of gastric diseases including atrophic gastritis, peptic ulcers, and gastric cancer. CagA is injected into host cells via a Type IV secretion system where it activates growth factor-like signaling, disrupts cell-ce...

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Detalles Bibliográficos
Autores principales: Reid, David W., Muyskens, Jonathan B., Neal, James T., Gaddini, Gino W., Cho, Lucy Y., Wandler, Anica M., Botham, Crystal M., Guillemin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417398/
https://www.ncbi.nlm.nih.gov/pubmed/22919616
http://dx.doi.org/10.3389/fcimb.2012.00024