Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist

BACKGROUND AND PURPOSE: Developmental switches in NMDA receptor subunit expression have been inferred from studies of GluN2 expression levels, changes in kinetics of glutamatergic synaptic currents and sensitivity of NMDA receptor-mediated currents to selective GluN2B antagonists. Here we use TCN 21...

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Detalles Bibliográficos
Autores principales: McKay, S, Griffiths, NH, Butters, PA, Thubron, EB, Hardingham, GE, Wyllie, DJA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417419/
https://www.ncbi.nlm.nih.gov/pubmed/22022974
http://dx.doi.org/10.1111/j.1476-5381.2011.01748.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417419/
https://www.ncbi.nlm.nih.gov/pubmed/22022974
http://dx.doi.org/10.1111/j.1476-5381.2011.01748.x

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