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Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist

BACKGROUND AND PURPOSE: Developmental switches in NMDA receptor subunit expression have been inferred from studies of GluN2 expression levels, changes in kinetics of glutamatergic synaptic currents and sensitivity of NMDA receptor-mediated currents to selective GluN2B antagonists. Here we use TCN 21...

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Detalles Bibliográficos
Autores principales:	McKay, S, Griffiths, NH, Butters, PA, Thubron, EB, Hardingham, GE, Wyllie, DJA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417419/ https://www.ncbi.nlm.nih.gov/pubmed/22022974 http://dx.doi.org/10.1111/j.1476-5381.2011.01748.x

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