Cargando…

Rho/ROCK-dependent inhibition of 3T3-L1 adipogenesis by G-protein-deamidating dermonecrotic toxins: differential regulation of Notch1, Pref1/Dlk1, and β-catenin signaling

The dermonecrotic toxins from Pasteurella multocida (PMT), Bordetella (DNT), Escherichia coli (CNF1-3), and Yersinia (CNFY) modulate their G-protein targets through deamidation and/or transglutamination of an active site Gln residue, which results in activation of the G protein and its cognate downs...

Descripción completa

Detalles Bibliográficos
Autores principales: Bannai, Yuka, Aminova, Leila R., Faulkner, Melinda J., Ho, Mengfei, Wilson, Brenda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417509/
https://www.ncbi.nlm.nih.gov/pubmed/22919671
http://dx.doi.org/10.3389/fcimb.2012.00080