Biodistribution and endocytosis of ICAM-1-targeting antibodies versus nanocarriers in the gastrointestinal tract in mice

Drug delivery to the gastrointestinal (GI) tract is key for improving treatment of GI maladies, developing oral vaccines, and facilitating drug transport into circulation. However, delivery of formulations to the GI tract is hindered by pH changes, degradative enzymes, mucus, and peristalsis, leadin...

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Detalles Bibliográficos
Autores principales: Mane, Viraj, Muro, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418107/
https://www.ncbi.nlm.nih.gov/pubmed/22915850
http://dx.doi.org/10.2147/IJN.S34105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418107/
https://www.ncbi.nlm.nih.gov/pubmed/22915850
http://dx.doi.org/10.2147/IJN.S34105

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