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5-hydroxytryptamine (5-HT) reduces total peripheral resistance during chronic infusion: direct arterial mesenteric relaxation is not involved

Serotonin (5-hydroxytryptamine; 5-HT) delivered over 1 week results in a sustained fall in blood pressure in the sham and deoxycorticosterone acetate (DOCA)-salt rat. We hypothesized 5-HT lowers blood pressure through direct receptor-mediated vascular relaxation. In vivo, 5-HT reduced mean arterial...

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Detalles Bibliográficos
Autores principales: Davis, Robert Patrick, Pattison, Jill, Thompson, Janice M, Tiniakov, Ruslan, Scrogin, Karie E, Watts, Stephanie W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418156/
https://www.ncbi.nlm.nih.gov/pubmed/22559843
http://dx.doi.org/10.1186/1471-2210-12-4