Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA(1) receptor signalling in rat brain cryosections without affecting global LPA degradation

BACKGROUND: Lysophosphatidic acid (LPA) is a signalling phospholipid with multiple biological functions, mainly mediated through specific G protein-coupled receptors. Aberrant LPA signalling is being increasingly implicated in the pathology of common human diseases, such as arteriosclerosis and canc...

Descripción completa

Detalles Bibliográficos
Autores principales: Aaltonen, Niina, Lehtonen, Marko, Varonen, Katri, Goterris, Gemma Arrufat, Laitinen, Jarmo T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418163/
https://www.ncbi.nlm.nih.gov/pubmed/22686545
http://dx.doi.org/10.1186/1471-2210-12-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418163/
https://www.ncbi.nlm.nih.gov/pubmed/22686545
http://dx.doi.org/10.1186/1471-2210-12-7

Ejemplares similares