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Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness

BACKGROUND: Multiple immunotherapy approaches have improved adaptive anti-tumor immune responses in patients with early stage disease; however, results have been less dramatic when treating patients with late stage disease. These blunted responses are likely due to a host of factors, including chang...

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Detalles Bibliográficos
Autores principales: Predina, Jarrod D, Kapoor, Veena, Judy, Brendan F, Cheng, Guanjun, Fridlender, Zvi Gregory, Albelda, Steven M, Singhal, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418164/
https://www.ncbi.nlm.nih.gov/pubmed/22742411
http://dx.doi.org/10.1186/1756-8722-5-34