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Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness
BACKGROUND: Multiple immunotherapy approaches have improved adaptive anti-tumor immune responses in patients with early stage disease; however, results have been less dramatic when treating patients with late stage disease. These blunted responses are likely due to a host of factors, including chang...
Autores principales: | Predina, Jarrod D, Kapoor, Veena, Judy, Brendan F, Cheng, Guanjun, Fridlender, Zvi Gregory, Albelda, Steven M, Singhal, Sunil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418164/ https://www.ncbi.nlm.nih.gov/pubmed/22742411 http://dx.doi.org/10.1186/1756-8722-5-34 |
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