Gentamicin-loaded nanoparticles show improved antimicrobial effects towards Pseudomonas aeruginosa infection

Gentamicin is an aminoglycoside antibiotic commonly used for treating Pseudomonas infections, but its use is limited by a relatively short half-life. In this investigation, developed a controlled-release gentamicin formulation using poly(lactide-co-glycolide) (PLGA) nanoparticles. We demonstrate tha...

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Detalles Bibliográficos
Autores principales: Abdelghany, Sharif M, Quinn, Derek J, Ingram, Rebecca J, Gilmore, Brendan F, Donnelly, Ryan F, Taggart, Clifford C, Scott, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418173/
https://www.ncbi.nlm.nih.gov/pubmed/22915848
http://dx.doi.org/10.2147/IJN.S34341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418173/
https://www.ncbi.nlm.nih.gov/pubmed/22915848
http://dx.doi.org/10.2147/IJN.S34341

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