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Gentamicin-loaded nanoparticles show improved antimicrobial effects towards Pseudomonas aeruginosa infection
Gentamicin is an aminoglycoside antibiotic commonly used for treating Pseudomonas infections, but its use is limited by a relatively short half-life. In this investigation, developed a controlled-release gentamicin formulation using poly(lactide-co-glycolide) (PLGA) nanoparticles. We demonstrate tha...
Autores principales: | Abdelghany, Sharif M, Quinn, Derek J, Ingram, Rebecca J, Gilmore, Brendan F, Donnelly, Ryan F, Taggart, Clifford C, Scott, Christopher J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418173/ https://www.ncbi.nlm.nih.gov/pubmed/22915848 http://dx.doi.org/10.2147/IJN.S34341 |
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