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IL-3 and TNFα increase Thymic Stromal Lymphopoietin Receptor (TSLPR) expression on eosinophils and enhance TSLP-stimulated degranulation

BACKGROUND: Thymic stromal lymphopoietin (TSLP) and eosinophils are prominent components of allergic inflammation. Therefore, we sought to determine whether TSLP could activate eosinophils, focusing on measuring the regulation of TSLPR expression on eosinophils and degranulation in response to TSLP,...

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Detalles Bibliográficos
Autores principales: Cook, Ellen B, Stahl, James L, Schwantes, Elizabeth A, Fox, Kristen E, Mathur, Sameer K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418208/
https://www.ncbi.nlm.nih.gov/pubmed/22838633
http://dx.doi.org/10.1186/1476-7961-10-8