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Two Variants in the Fibulin2 Gene Are Associated with Lower Systolic Blood Pressure and Decreased Risk of Hypertension

Arterial stiffness is an important factor in hypertension. Fibulin 2 is an extracellular matrix scaffold protein involved in arterial stiffness and, hence, the fibulin 2 (FBLN2) gene may be a candidate for hypertension susceptibility. 4 single nucleotide polymorphisms (SNPs) of FBLN2 were evaluated...

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Detalles Bibliográficos
Autores principales: Vallvé, Joan-Carles, Serra, Noemí, Zalba, Guillermo, Fortuño, Ana, Beloqui, Óscar, Ferre, Raimon, Ribalta, Josep, Masana, Lluís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418224/
https://www.ncbi.nlm.nih.gov/pubmed/22912785
http://dx.doi.org/10.1371/journal.pone.0043051