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Overexpression of Guanylate Cyclase Activating Protein 2 in Rod Photoreceptors In Vivo Leads to Morphological Changes at the Synaptic Ribbon

Guanylate cyclase activating proteins are EF-hand containing proteins that confer calcium sensitivity to retinal guanylate cyclase at the outer segment discs of photoreceptor cells. By making the rate of cGMP synthesis dependent on the free intracellular calcium levels set by illumination, GCAPs pla...

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Detalles Bibliográficos
Autores principales: López-del Hoyo, Natalia, Fazioli, Lucrezia, López-Begines, Santiago, Fernández-Sánchez, Laura, Cuenca, Nicolás, Llorens, Jordi, de la Villa, Pedro, Méndez, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418235/
https://www.ncbi.nlm.nih.gov/pubmed/22912773
http://dx.doi.org/10.1371/journal.pone.0042994