Silencing of GPNMB by siRNA Inhibits the Formation of Melanosomes in Melanocytes in a MITF-Independent Fashion

BACKGROUND: Melanosomes are specialized membrane-surrounded organelles, which are involved in the synthesis, storage and transport of melanin. Glycoprotein (transmembrane) non-metastatic melanoma protein b (GPNMB), a melanosome-specific structural protein, shares significant amino acid sequence homo...

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Detalles Bibliográficos
Autores principales: Zhang, Ping, Liu, Wei, Zhu, Cansheng, Yuan, Xiaoying, Li, Dongguang, Gu, Weijie, Ma, Huimin, Xie, Xin, Gao, Tianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418242/
https://www.ncbi.nlm.nih.gov/pubmed/22912767
http://dx.doi.org/10.1371/journal.pone.0042955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418242/
https://www.ncbi.nlm.nih.gov/pubmed/22912767
http://dx.doi.org/10.1371/journal.pone.0042955

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