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Interaction between Smoking and HLA-DRB1*04 Gene Is Associated with a High Cardiovascular Risk in Brazilian Amazon Patients with Rheumatoid Arthritis

BACKGROUND: Rheumatoid Arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints that affects approximately 1% of the population worldwide. The HLA-DRB1 gene locus plays a major role in genetic susceptibility to RA, a condition that has been associated with a high c...

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Detalles Bibliográficos
Autores principales: Boechat, Narjara de Oliveira, Ogusku, Mauricio Morish, Boechat, Antonio Luiz, Sadahiro, Aya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418250/
https://www.ncbi.nlm.nih.gov/pubmed/22912672
http://dx.doi.org/10.1371/journal.pone.0041588