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Dyskerin Overexpression in Human Hepatocellular Carcinoma Is Associated with Advanced Clinical Stage and Poor Patient Prognosis

BACKGROUND: Dyskerin (encoded by the DKC1 gene) is an essential nucleolar protein involved in cell proliferation, where it is required for the pseudo-uridylation of ribosomal RNA (rRNA) molecules and the stabilization of the telomerase RNA component. Dyskerin expression has been reported to predict...

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Detalles Bibliográficos
Autores principales: Liu, Bei, Zhang, Jinglei, Huang, Chen, Liu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418259/
https://www.ncbi.nlm.nih.gov/pubmed/22912812
http://dx.doi.org/10.1371/journal.pone.0043147