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Modified Recombinant Proteins Can Be Exported via the Sec Pathway in Escherichia coli
The correct folding of a protein is a pre-requirement for its proper posttranslational modification. The Escherichia coli Sec pathway, in which preproteins, in an unfolded, translocation-competent state, are rapidly secreted across the cytoplasmic membrane, is commonly assumed to be unfavorable for...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418276/ https://www.ncbi.nlm.nih.gov/pubmed/22912705 http://dx.doi.org/10.1371/journal.pone.0042519 |