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Apoptosis and Autophagy in Breast Cancer Cells following Exemestane Treatment

Aromatase inhibitors (AIs), which block the conversion of androgens to estrogens, are used for hormone-dependent breast cancer treatment. Exemestane, a steroidal that belongs to the third-generation of AIs, is a mechanism-based inhibitor that binds covalently and irreversibly, inactivating and desta...

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Detalles Bibliográficos
Autores principales: Amaral, Cristina, Borges, Margarida, Melo, Soraia, da Silva, Elisiário Tavares, Correia-da-Silva, Georgina, Teixeira, Natércia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418278/
https://www.ncbi.nlm.nih.gov/pubmed/22912703
http://dx.doi.org/10.1371/journal.pone.0042398