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Apoptosis and Autophagy in Breast Cancer Cells following Exemestane Treatment
Aromatase inhibitors (AIs), which block the conversion of androgens to estrogens, are used for hormone-dependent breast cancer treatment. Exemestane, a steroidal that belongs to the third-generation of AIs, is a mechanism-based inhibitor that binds covalently and irreversibly, inactivating and desta...
Autores principales: | Amaral, Cristina, Borges, Margarida, Melo, Soraia, da Silva, Elisiário Tavares, Correia-da-Silva, Georgina, Teixeira, Natércia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418278/ https://www.ncbi.nlm.nih.gov/pubmed/22912703 http://dx.doi.org/10.1371/journal.pone.0042398 |
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