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Group Normalization for Genomic Data

Data normalization is a crucial preliminary step in analyzing genomic datasets. The goal of normalization is to remove global variation to make readings across different experiments comparable. In addition, most genomic loci have non-uniform sensitivity to any given assay because of variation in loc...

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Detalles Bibliográficos
Autores principales: Ghandi, Mahmoud, Beer, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418286/
https://www.ncbi.nlm.nih.gov/pubmed/22912661
http://dx.doi.org/10.1371/journal.pone.0038695