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Quetiapine, an Atypical Antipsychotic, Is Protective against Autoimmune-Mediated Demyelination by Inhibiting Effector T Cell Proliferation

Quetiapine (Que), a commonly used atypical antipsychotic drug (APD), can prevent myelin from breakdown without immune attack. Multiple sclerosisis (MS), an autoimmune reactive inflammation demyelinating disease, is triggered by activated myelin-specific T lymphocytes (T cells). In this study, we inv...

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Detalles Bibliográficos
Autores principales: Mei, Feng, Guo, Sheng, He, Yangtao, Wang, Linyun, Wang, Hongkai, Niu, Jianqin, Kong, Jiming, Li, Xinmin, Wu, Yuzhang, Xiao, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418290/
https://www.ncbi.nlm.nih.gov/pubmed/22912731
http://dx.doi.org/10.1371/journal.pone.0042746