Cargando…
Quetiapine, an Atypical Antipsychotic, Is Protective against Autoimmune-Mediated Demyelination by Inhibiting Effector T Cell Proliferation
Quetiapine (Que), a commonly used atypical antipsychotic drug (APD), can prevent myelin from breakdown without immune attack. Multiple sclerosisis (MS), an autoimmune reactive inflammation demyelinating disease, is triggered by activated myelin-specific T lymphocytes (T cells). In this study, we inv...
Autores principales: | Mei, Feng, Guo, Sheng, He, Yangtao, Wang, Linyun, Wang, Hongkai, Niu, Jianqin, Kong, Jiming, Li, Xinmin, Wu, Yuzhang, Xiao, Lan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418290/ https://www.ncbi.nlm.nih.gov/pubmed/22912731 http://dx.doi.org/10.1371/journal.pone.0042746 |
Ejemplares similares
-
Quetiapine Inhibits Microglial Activation by Neutralizing Abnormal STIM1-Mediated Intercellular Calcium Homeostasis and Promotes Myelin Repair in a Cuprizone-Induced Mouse Model of Demyelination
por: Wang, Hanzhi, et al.
Publicado: (2015) -
The use of atypical antipsychotics beyond psychoses: efficacy of quetiapine in bipolar disorder
por: Mundo, Emanuela, et al.
Publicado: (2006) -
Effects of Atypical Antipsychotics, Clozapine, Quetiapine and Brexpiprazole on Astroglial Transmission Associated with Connexin43
por: Fukuyama, Kouji, et al.
Publicado: (2021) -
Quetiapine Attenuates Schizophrenia-Like Behaviors and Demyelination in a MK-801–Induced Mouse Model of Schizophrenia
por: He, Jue, et al.
Publicado: (2020) -
The Added Value of Liquid Antipsychotics: The Case of Quetiapine
por: Papazisis, Georgios, et al.
Publicado: (2019)