Targeted and Reversible Blood-Retinal Barrier Disruption via Focused Ultrasound and Microbubbles

The blood-retinal barrier (BRB) prevents most systemically-administered drugs from reaching the retina. This study investigated whether burst ultrasound applied with a circulating microbubble agent can disrupt the BRB, providing a noninvasive method for the targeted delivery of systemically administ...

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Detalles Bibliográficos
Autores principales: Park, Juyoung, Zhang, Yongzhi, Vykhodtseva, Natalia, Akula, James D., McDannold, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418291/
https://www.ncbi.nlm.nih.gov/pubmed/22912733
http://dx.doi.org/10.1371/journal.pone.0042754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418291/
https://www.ncbi.nlm.nih.gov/pubmed/22912733
http://dx.doi.org/10.1371/journal.pone.0042754

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