SERPINA1 PiZ and PiS Heterozygotes and Lung Function Decline in the SAPALDIA Cohort

BACKGROUND: Severe alpha1-antitrypsin (AAT) deficiency is a strong risk factor for COPD. But the impact of gene variants resulting in mild or intermediate AAT deficiency on the longitudinal course of respiratory health remains controversial. There is indication from experimental studies that pro-inf...

Descripción completa

Detalles Bibliográficos
Autores principales: Thun, Gian-Andri, Ferrarotti, Ilaria, Imboden, Medea, Rochat, Thierry, Gerbase, Margaret, Kronenberg, Florian, Bridevaux, Pierre-Olivier, Zemp, Elisabeth, Zorzetto, Michele, Ottaviani, Stefania, Russi, Erich W., Luisetti, Maurizio, Probst-Hensch, Nicole M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418297/
https://www.ncbi.nlm.nih.gov/pubmed/22912729
http://dx.doi.org/10.1371/journal.pone.0042728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418297/
https://www.ncbi.nlm.nih.gov/pubmed/22912729
http://dx.doi.org/10.1371/journal.pone.0042728

Ejemplares similares