Cargando…

SERPINA1 PiZ and PiS Heterozygotes and Lung Function Decline in the SAPALDIA Cohort

BACKGROUND: Severe alpha1-antitrypsin (AAT) deficiency is a strong risk factor for COPD. But the impact of gene variants resulting in mild or intermediate AAT deficiency on the longitudinal course of respiratory health remains controversial. There is indication from experimental studies that pro-inf...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thun, Gian-Andri, Ferrarotti, Ilaria, Imboden, Medea, Rochat, Thierry, Gerbase, Margaret, Kronenberg, Florian, Bridevaux, Pierre-Olivier, Zemp, Elisabeth, Zorzetto, Michele, Ottaviani, Stefania, Russi, Erich W., Luisetti, Maurizio, Probst-Hensch, Nicole M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418297/ https://www.ncbi.nlm.nih.gov/pubmed/22912729 http://dx.doi.org/10.1371/journal.pone.0042728

Ejemplares similares

Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study
por: Imboden, Medea, et al.
Publicado: (2007)

Improved Air Quality and Attenuated Lung Function Decline: Modification by Obesity in the SAPALDIA Cohort
por: Schikowski, Tamara, et al.
Publicado: (2013)

Depression and cardiovascular disease are not linked by high blood pressure: findings from the SAPALDIA cohort
por: Obas, Katrina A., et al.
Publicado: (2022)

Modification of the Association between PM(10) and Lung Function Decline by Cadherin 13 Polymorphisms in the SAPALDIA Cohort: A Genome-Wide Interaction Analysis
por: Imboden, Medea, et al.
Publicado: (2014)

Heterozygous Genotype rs17580 AT (PiS) in SERPINA1 is Associated with COPD Secondary to Biomass-Burning and Tobacco Smoking: A Case–Control and Populational Study
por: Pérez-Rubio, Gloria, et al.
Publicado: (2020)

Circulating alpha1-antitrypsin in the general population: Determinants and association with lung function
por: Senn, Oliver, et al.
Publicado: (2008)

Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels
por: Thun, Gian Andri, et al.
Publicado: (2013)

Identification and characterisation of eight novel SERPINA1 Null mutations
por: Ferrarotti, Ilaria, et al.
Publicado: (2014)

Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study
por: Eze, Ikenna C, et al.
Publicado: (2017)

Endotoxin receptor CD14 in PiZ α-1-antitrypsin deficiency individuals
por: Sandström, Caroline S, et al.
Publicado: (2008)

Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study
por: Eze, Ikenna C., et al.
Publicado: (2020)

Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)
por: Imboden, M, et al.
Publicado: (2006)

The SAPALDIA cohort: design and results in the field of respiratory and cardio-vascular diseases
por: Rochat, T
Publicado: (2013)

PiZ Mouse Liver Accumulates Polyubiquitin Conjugates That Associate with Catalytically Active 26S Proteasomes
por: Haddock, Christopher J., et al.
Publicado: (2014)

Accelerated decline in lung function in smoking women with airway obstruction: SAPALDIA 2 cohort study
por: Downs, Sara H, et al.
Publicado: (2005)

Heart Rate Variability in Association with Frequent Use of Household Sprays and Scented Products in SAPALDIA
por: Mehta, Amar J., et al.
Publicado: (2012)

Nephrolithiasis and renal failure among patients exposed to atazanavir, other PIs and PI-free regimens
por: Nkhoma, Ella, et al.
Publicado: (2014)

The E3 Ligase APIP10 Connects the Effector AvrPiz-t to the NLR Receptor Piz-t in Rice
por: Park, Chan Ho, et al.
Publicado: (2016)

Liver-Humanized NSG-PiZ Mice Support the Study of Chronic Hepatitis B Virus Infection and Antiviral Therapies
por: Colón-Thillet, Rossana, et al.
Publicado: (2023)

High Serum Level of IL-17 in Patients with Chronic Obstructive Pulmonary Disease and the Alpha-1 Antitrypsin PiZ Allele
por: Pervakova, Margarita Y., et al.
Publicado: (2020)

Long-Lasting Protection of Activity of Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors (PIs) by Boosted PI Containing Regimens
por: Scherrer, Alexandra U., et al.
Publicado: (2012)

Long-Term Exposure to Ambient Air Pollution and Metabolic Syndrome in Adults
por: Eze, Ikenna C., et al.
Publicado: (2015)

Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency
por: Li, Yanfeng, et al.
Publicado: (2023)

Different Genes Interact with Particulate Matter and Tobacco Smoke Exposure in Affecting Lung Function Decline in the General Population
por: Curjuric, Ivan, et al.
Publicado: (2012)

Correction: Long-Lasting Protection of Activity of Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors (PIs) by Boosted PI Containing Regimens
por: Scherrer, Alexandra U., et al.
Publicado: (2013)

A survey of new PIs in the UK
por: Acton, Sophie E, et al.
Publicado: (2019)

Reference values for methacholine reactivity (SAPALDIA study)
por: Jayet, Pierre-Yves, et al.
Publicado: (2005)

Associations of Novel and Traditional Vascular Biomarkers of Arterial Stiffness: Results of the SAPALDIA 3 Cohort Study
por: Endes, Simon, et al.
Publicado: (2016)

A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM(10) exposure and diabetes
por: Eze, Ikenna C., et al.
Publicado: (2016)

Decreased PM(10) Exposure Attenuates Age-Related Lung Function Decline: Genetic Variants in p53, p21, and CCND1 Modify This Effect
por: Imboden, Medea, et al.
Publicado: (2009)

The prevalence of PI(∗)S and PI(∗)Z SERPINA1 alleles in healthy individuals and COPD patients in Saudi Arabia: A case–control study
por: Al-Jameil, Noura, et al.
Publicado: (2017)

Biobanking across the phenome - at the center of chronic disease research
por: Imboden, Medea, et al.
Publicado: (2013)

Enabling ATLAS big data processing on Piz Daint at CSCS
por: Sciacca, Francesco Giovanni, et al.
Publicado: (2019)

Enabling ATLAS big data processing on Piz Daint at CSCS
por: Sciacca, Francesco Giovanni, et al.
Publicado: (2020)

Carotid Stiffness and Physical Activity in Elderly—A Short Report of the SAPALDIA 3 Cohort Study
por: Caviezel, Seraina, et al.
Publicado: (2015)

DPM PERFORMANCE TESTING USING RASPBERRY PIS
por: Regala, M
Publicado: (2013)

SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts
por: Beckmeyer-Borowko, Anna, et al.
Publicado: (2018)

Novel Variation and Evolution of AvrPiz-t of Magnaporthe oryzae in Field Isolates
por: Wang, Qun, et al.
Publicado: (2020)

Screening for Alpha 1 antitrypsin deficiency in Tunisian subjects with obstructive lung disease: a feasibility report
por: Denden, Sabri, et al.
Publicado: (2009)

Magnetic measurements on PIS MH 42 Lead ion
por: Borburgh, J
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_7utuahekj9lki309te9arlpi2j