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NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum
Nascent polypeptide-associated complex (NAC) was initially found to bind to any segment of the nascent chain except signal sequences. In this way, NAC is believed to prevent mistargeting due to binding of signal recognition particle (SRP) to signalless ribosome nascent chain complexes (RNCs). Here w...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418300/ https://www.ncbi.nlm.nih.gov/pubmed/22740632 http://dx.doi.org/10.1091/mbc.E12-02-0112 |