NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum

Nascent polypeptide-associated complex (NAC) was initially found to bind to any segment of the nascent chain except signal sequences. In this way, NAC is believed to prevent mistargeting due to binding of signal recognition particle (SRP) to signalless ribosome nascent chain complexes (RNCs). Here w...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Berndt, Uta, Gölz, Hanna, Tais, Arlette, Oellerer, Stefan, Wölfle, Tina, Fitzke, Edith, Rospert, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418300/
https://www.ncbi.nlm.nih.gov/pubmed/22740632
http://dx.doi.org/10.1091/mbc.E12-02-0112

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