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Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish

In our effort to understand genetic disorders of the photoreceptor cells of the retina, we have focused on intraflagellar transport in photoreceptor sensory cilia. From previous mouse proteomic data we identified a cilia protein Ttc26, orthologue of dyf-13 in Caenorhabditis elegans, as a target. We...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Liu, Qin, Austin, Chrissy, Drummond, Iain, Pierce, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418303/
https://www.ncbi.nlm.nih.gov/pubmed/22718903
http://dx.doi.org/10.1091/mbc.E12-01-0019