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Live-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control

We developed a system to monitor periodic luciferase activity from cell cycle–regulated promoters in synchronous cells. Reporters were driven by a minimal human E2F1 promoter with peak expression in G1/S or a basal promoter with six Forkhead DNA-binding sites with peak expression at G2/M. After cell...

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Detalles Bibliográficos
Autores principales: Grant, Gavin D., Gamsby, Joshua, Martyanov, Viktor, Brooks, Lionel, George, Lacy K., Mahoney, J. Matthew, Loros, Jennifer J., Dunlap, Jay C., Whitfield, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418304/
https://www.ncbi.nlm.nih.gov/pubmed/22740631
http://dx.doi.org/10.1091/mbc.E11-02-0170