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Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a

BACKGROUND: Activation signals can be negatively regulated by cell surface receptors bearing immunoreceptor tyrosine-based inhibitory motifs (ITIMs). CD300a, an ITIM bearing type I transmembrane protein, is expressed on many hematopoietic cells, including subsets of lymphocytes. RESULTS: We have tak...

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Detalles Bibliográficos
Autores principales: DeBell, Karen E, Simhadri, Venkateswara R, Mariano, John L, Borrego, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418551/
https://www.ncbi.nlm.nih.gov/pubmed/22537350
http://dx.doi.org/10.1186/1471-2172-13-23