LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner

BACKGROUND: Compelling evidence has implicated neuroinflammation in the pathogenesis of a number of neurodegenerative conditions. Chronic activation of both astrocytes and microglia leads to excessive secretion of proinflammatory molecules such as TNFα, IL-6 and IL-1β with potentially deleterious co...

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Detalles Bibliográficos
Autores principales: Minogue, Aedín M, Barrett, James P, Lynch, Marina A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418561/
https://www.ncbi.nlm.nih.gov/pubmed/22697788
http://dx.doi.org/10.1186/1742-2094-9-126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418561/
https://www.ncbi.nlm.nih.gov/pubmed/22697788
http://dx.doi.org/10.1186/1742-2094-9-126

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