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LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner

BACKGROUND: Compelling evidence has implicated neuroinflammation in the pathogenesis of a number of neurodegenerative conditions. Chronic activation of both astrocytes and microglia leads to excessive secretion of proinflammatory molecules such as TNFα, IL-6 and IL-1β with potentially deleterious co...

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Detalles Bibliográficos
Autores principales:	Minogue, Aedín M, Barrett, James P, Lynch, Marina A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418561/ https://www.ncbi.nlm.nih.gov/pubmed/22697788 http://dx.doi.org/10.1186/1742-2094-9-126

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