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Heterologous protection elicited by candidate monomeric recombinant HIV-1 gp120 vaccine in the absence of cross neutralising antibodies in a macaque model

BACKGROUND: Current data suggest that an efficacious human immunodeficiency virus type 1 (HIV-1) vaccine should elicit both adaptive humoral and cell mediated immune responses. Such a vaccine will also need to protect against infection from a range of heterologous viral variants. Here we have develo...

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Detalles Bibliográficos
Autores principales: Page, Mark, Stebbings, Richard, Berry, Neil, Hull, Robin, Ferguson, Deborah, Davis, Leanne, Duffy, Laura, Elsley, William, Hall, Joanna, Ham, Claire, Hassall, Mark, Li, Bo, Mee, Edward T, Quartey-Papafio, Ruby, Rose, Nicola J, Mathy, Nathalie, Voss, Gerald, Stott, E James, Almond, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418562/
https://www.ncbi.nlm.nih.gov/pubmed/22799593
http://dx.doi.org/10.1186/1742-4690-9-56