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The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity

BACKGROUND: Phosphatidylserine receptor is a key molecule that mediates the phagocytosis of apoptotic cells. Milk fat globule-EGF factor 8 (MFG-E8) is a phosphatidylserine receptor that is expressed on various macrophage lineage cells, including microglia in the central nervous system (CNS). Targete...

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Detalles Bibliográficos
Autores principales: Li, Endong, Noda, Mariko, Doi, Yukiko, Parajuli, Bijay, Kawanokuchi, Jun, Sonobe, Yoshifumi, Takeuchi, Hideyuki, Mizuno, Tetsuya, Suzumura, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418568/
https://www.ncbi.nlm.nih.gov/pubmed/22742657
http://dx.doi.org/10.1186/1742-2094-9-148