Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin

BACKGROUND: Intact myelin, which normally surrounds axons, breaks down in Wallerian degeneration following axonal injury and during neurodegenerative diseases such as multiple sclerosis. Clearance of degenerated myelin by phagocytosis is essential since myelin impedes repair and exacerbates damage....

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Detalles Bibliográficos
Autores principales: Hadas, Smadar, Spira, Maya, Hanisch, Uwe-Karsten, Reichert, Fanny, Rotshenker, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418574/
https://www.ncbi.nlm.nih.gov/pubmed/22776089
http://dx.doi.org/10.1186/1742-2094-9-166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418574/
https://www.ncbi.nlm.nih.gov/pubmed/22776089
http://dx.doi.org/10.1186/1742-2094-9-166

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