Cargando…

Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity

BACKGROUND: Plasminogen activator inhibitor type 1 (PAI-1) is the primary inhibitor of urokinase type plasminogen activators (uPA) and tissue type plasminogen activators (tPA), which mediate fibrinolysis. PAI-1 is also involved in the innate immunity by regulating cell migration and phagocytosis. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeon, Hyejin, Kim, Jong-Heon, Kim, Jae-Hong, Lee, Won-Ha, Lee, Myung-Shik, Suk, Kyoungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418576/
https://www.ncbi.nlm.nih.gov/pubmed/22747686
http://dx.doi.org/10.1186/1742-2094-9-149