Reversion of P-Glycoprotein-Mediated Multidrug Resistance in Human Leukemic Cell Line by Diallyl Trisulfide

Multidrug resistance (MDR) is the major obstacle in chemotherapy, which involves multiple signaling pathways. Diallyl trisulfide (DATS) is the main sulfuric compound in garlic. In the present study, we aimed to explore whether DATS could overcome P-glycoprotein-(P-gp-)mediated MDR in K562/A02 cells,...

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Detalles Bibliográficos
Autores principales: Xia, Qing, Wang, Zhi-Yong, Li, Hui-Qing, Diao, Yu-Tao, Li, Xiao-Li, Cui, Jia, Chen, Xue-Liang, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418761/
https://www.ncbi.nlm.nih.gov/pubmed/22919419
http://dx.doi.org/10.1155/2012/719805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418761/
https://www.ncbi.nlm.nih.gov/pubmed/22919419
http://dx.doi.org/10.1155/2012/719805

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