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Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas

To clarify the significance of DNA methylation alterations during renal carcinogenesis, methylome analysis using single-CpG-resolution Infinium array was performed on 29 normal renal cortex tissue (C) samples, 107 non-cancerous renal cortex tissue (N) samples obtained from patients with clear cell r...

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Detalles Bibliográficos
Autores principales: Arai, Eri, Chiku, Suenori, Mori, Taisuke, Gotoh, 
Masahiro, Nakagawa, Tohru, Fujimoto, 
Hiroyuki, Kanai, Yae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418891/
https://www.ncbi.nlm.nih.gov/pubmed/22610075
http://dx.doi.org/10.1093/carcin/bgs177