Improvement of cardiac function and reversal of gap junction remodeling by Neuregulin-1β in volume-overloaded rats with heart failure

OBJECTIVE: We performed experiments using Neuregulin-1β (NRG-1β) treatment to determine a mechanism for the protective role derived from its beneficial effects by remodeling gap junctions (GJs) during heart failure (HF). METHODS: Rat models of HF were established by aortocaval fistula. Forty-eight r...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xue-Hui, Zhuo, Xiao-Zhen, Ni, Ya-Juan, Gong, Min, Wang, Ting-Zhong, Lu, Qun, Ma, Ai-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418908/
https://www.ncbi.nlm.nih.gov/pubmed/22916065
http://dx.doi.org/10.3724/SP.J.1263.2012.03271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418908/
https://www.ncbi.nlm.nih.gov/pubmed/22916065
http://dx.doi.org/10.3724/SP.J.1263.2012.03271

Ejemplares similares