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Improvement of cardiac function and reversal of gap junction remodeling by Neuregulin-1β in volume-overloaded rats with heart failure

OBJECTIVE: We performed experiments using Neuregulin-1β (NRG-1β) treatment to determine a mechanism for the protective role derived from its beneficial effects by remodeling gap junctions (GJs) during heart failure (HF). METHODS: Rat models of HF were established by aortocaval fistula. Forty-eight r...

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Detalles Bibliográficos
Autores principales:	Wang, Xue-Hui, Zhuo, Xiao-Zhen, Ni, Ya-Juan, Gong, Min, Wang, Ting-Zhong, Lu, Qun, Ma, Ai-Qun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Science Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418908/ https://www.ncbi.nlm.nih.gov/pubmed/22916065 http://dx.doi.org/10.3724/SP.J.1263.2012.03271

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