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Rosuvastatin inhibits the smooth muscle cell proliferation by targeting TNFα mediated Rho kinase pathway

OBJECTIVE: To investigate whether Tumor Necrosis Factor-alpha (TNFα) is capable of activating Rho kinase pathway which leads to smooth muscle cell proliferation and the intervention function of Rosuvastatin, and clarify the mechanism and intervention manner of anti-atherosclerosis by Rosuvastatin. M...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Tong, Hao, Zhang, Man, Wang, Xiao-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418909/
https://www.ncbi.nlm.nih.gov/pubmed/22916066
http://dx.doi.org/10.3724/SP.J.1263.2012.03301