Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells

Most ovarian cancers originate from the ovarian surface epithelium and are characterized by aneuploid karyotypes. Aneuploidy, a consequence of chromosome instability, is an early event during the development of ovarian cancers. However, how aneuploid cells are evolved from normal diploid cells in ov...

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Detalles Bibliográficos
Autores principales: Lv, Lei, Zhang, Tianwei, Yi, Qiyi, Huang, Yun, Wang, Zheng, Hou, Heli, Zhang, Huan, Zhang, Wei, Hao, Qiaomei, Guo, Zongyou, Cooke, Howard J., Shi, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419060/
https://www.ncbi.nlm.nih.gov/pubmed/22801546
http://dx.doi.org/10.4161/cc.21196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419060/
https://www.ncbi.nlm.nih.gov/pubmed/22801546
http://dx.doi.org/10.4161/cc.21196

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