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Application of a case–control study design to investigate genotypic signatures of HIV-1 transmission

BACKGROUND: The characterization of HIV-1 transmission strains may inform the design of an effective vaccine. Shorter variable loops with fewer predicted glycosites have been suggested as signatures enriched in envelope sequences derived during acute HIV-1 infection. Specifically, a transmission-lin...

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Detalles Bibliográficos
Autores principales: Mota, Talia M, Murray, John M, Center, Rob J, Purcell, Damian F J, McCaw, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419081/
https://www.ncbi.nlm.nih.gov/pubmed/22731404
http://dx.doi.org/10.1186/1742-4690-9-54