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CK2 as anti-stress factor

Misfolded proteins are prone to form aggregates, which interfere with normal cellular functions. In general, the ubiquitin-proteasome system degrades such misfolded proteins to avoid aggregation. If this system becomes impaired or overloaded, an inclusion-body-like organelle, aggresome will operate....

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Detalles Bibliográficos
Autores principales: Watabe, Masahiko, Nakaki, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419114/
https://www.ncbi.nlm.nih.gov/pubmed/22896792
http://dx.doi.org/10.4161/cib.19473